Mmaf
MMAF hydrochloride (Cat No.:I013918) is an anti tubulin polymerization inhibitor that can effectively inhibit cell division and is mainly used as an anti-tumor drug. MMAF hydrochloride is widely used as a cytotoxic component of antibody coupled drugs (ADCs).
Mmaf Property
| Molecular Formula: | C₃₉H₆₆ClN₅O₈ |
|---|---|
| Molecular Weight: | 768.42 |
| Target: | Microtubule/TubulinADC Cytotoxin |
| Solubility: | DMSO: 27 mg/mL |
| Purity: | ≥95% |
Mmaf Computed Descriptor
| IUPAC Name: | (2S)-2-[[(2R,3R)-3-methoxy-3-[(2S)-1-[(3R,4S,5S)-3-methoxy-5-methyl-4-[methyl-[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]amino]heptanoyl]pyrrolidin-2-yl]-2-methylpropanoyl]amino]-3-phenylpropanoic acid;hydrochloride |
|---|---|
| InChI: | InChI=1S/C39H65N5O8.ClH/c1-12-25(6)34(43(9)38(48)33(24(4)5)42-37(47)32(40-8)23(2)3)30(51-10)22-31(45)44-20-16-19-29(44)35(52-11)26(7)36(46)41-28(39(49)50)21-27-17-14-13-15-18-27;/h13-15,17-18,23-26,28-30,32-35,40H,12,16,19-22H2,1-11H3,(H,41,46)(H,42,47)(H,49,50);1H/t25-,26+,28-,29-,30+,32-,33-,34-,35+;/m0./s1 |
| InChIKey: | BUPKFQQDMNUXOY-KMYLZLQDSA-N |
| SMILES: | CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(CC2=CC=CC=C2)C(=O)O)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)NC.Cl |
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