Dihexa
Dihexa(CAT: R029524) is an oligopeptide derived from angiotensin Ⅳ. It has a high affinity with hepatocyte growth factor and therefore has the good binding activity to the C-Met receptor. Currently, it is mainly used in the research of adjunctive therapy for Alzheimer’s disease. This product is used for medical research and development and other scientific research purposes.
| Synonyms: | N-(1-Oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-L-isoleucinamide |
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Dihexa Property
| Molecular Formula: | C27 H44 N4 O5 |
|---|---|
| Molecular Weight: | 504.66 |
| Purity: | ≥95% |
| Storage: | Desiccate at +4C |
Dihexa Computed Descriptor
| IUPAC Name: | (2S,3S)-N-(6-amino-6-oxohexyl)-2-[[(2S)-2-(hexanoylamino)-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanamide |
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| InChI: | InChI=1S/C27H44N4O5/c1-4-6-8-12-24(34)30-22(18-20-13-15-21(32)16-14-20)26(35)31-25(19(3)5-2)27(36)29-17-10-7-9-11-23(28)33/h13-16,19,22,25,32H,4-12,17-18H2,1-3H3,(H2,28,33)(H,29,36)(H,30,34)(H,31,35)/t19-,22-,25-/m0/s1 |
| InChIKey: | XEUVNVNAVKZSPT-JTJYXVOQSA-N |
| SMILES: | O=C(N)CCCCCNC([[email protected]@H](NC([[email protected]@H](NC(CCCCC)=O)CC1=CC=C(O)C=C1)=O)[[email protected]@H](C)CC)=O |
DIHEXA: WHAT IS THIS PEPTIDE ALL ABOUT?
Dihexa is known to be N-hexanoic-Tyr-ile-(6) aminohexanoic amide. Its developmental code name is known to be PNB-0408.
This drug is an oligopeptide drug that has been derived from angiotensin IV. With its high binding affinity to hepatocyte growth (HGF) and its receptor c-Met, Dihexa is a small peptide that has been developed by researchers from Washington State University.
This was done to discover its potentials on cognitive functions of potential trauma brain disorders- This includes Alzheimer’s Disease. This is done through increased synaptogenesis.
It has been found out that this peptide had seven orders of magnitude, which is more potent than the brain-derived neurotrophic factor.
It’s famously called “the neurogenic wonder-drug” because of the amazing wonders it contributes. This is even ten million times stronger than the BDNF or the Brain-derived neurotrophic factor, which is considered the leading medication for synapse formation.
Clinical studies have even shown through animal models of Disease, enhancing:
- Acquisition
- Consolidation
- And also recall of learning and memory
DIHEXA’S CONTENT AND POTENCY
In cream form, Dihexa is offered in 20mg/mL, provided in the form of the transdermal cream. It has a 30mL applicator.
For the capsule, it is offered in 10 mg and 20mg oral capsules.
DIHEXA’S SUGGESTED DOSAGE
For the cream, apply 0.5-1mL (or 2-4 clicks) to your inner forearm daily and rub it in until it is absorbed.
For capsules, you may take 1 tablet by mouth per day.
HOW DOES DIHEXA WORK?
Being a first-class compound that is orally active, Dihexa works through penetrating the blood-brain barriers. This also works through facilitating one’s memory consolidation and even memory retrieval.
Researchers have seen how this peptide is very active. It also shows a very promising characteristic in terms of overcoming any memory and motor dysfunction.
THE BENEFITS OF DIHEXA
As a new drug, Dihexa has been highly seen to help people experiencing Alzheimer’s Disease.
Thus, it’s main function is to relieve and supplement people who are stricken by this Disease to slow down the progression of Alzheimer’s.
The best thing about Dihexa is its ability to be able to repair damages found in the synapse that is just between the neurons.
Here are some of the benefits of Dihexa:
- Helps people having Alzheimer’s Disease and those with Parkinson’s Disease
- Can increase your mental stamina
- Can improve creative thinking skills
- Can enhance conversational skills
- Can improve one’s ability to solve problems
- Can help in managing depression
- Improves memory
Dihexa also helps one improve focus and learning. That’s why this is good most, especially for people who study too.
It can even improve heart health, and also boost medical endurance.
People who use Dihexa have had testimonies of how this peptide has helped improve their creativity, thinking, and even problem-solving skills.
Although you must keep in mind that despite the benefits of Dihexa, it still has some side effects that you must be aware of primarily when it is being regularly used.
One who even stops using Dihexa can have severe withdrawal effects once they decide to discontinue using this peptide. Some side effects could be unexpected jitters or even irritability.
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